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Every week, Maxwell Award-winner, Heisman Trophy finalist, former NFL starting quarterback and CBS Sports analyst Brady Quinn will be here offering his picks on some of the closest, most-competitive college football games.

We have already seen some surprises, but you can set your mind at ease this weekend with these straight-up winners.

Florida State at Louisville: The Cardinals took the Seminoles to the wire last time they visited Papa Johns Stadium. One of the biggest differences with this FSU team is it will not be led by former Heisman Trophy winner Jameis Winston, who overcame a 21-0 first-half deficit that night. Florida State phenom Deondre Francois will lead the charge with a running back who’s familiar with the environment in Dalvin Cook. But this Louisville team is different from years past. These Cardinals are led by a legitimate Heisman candidate in QB Lamar Jackson and have a defense that appears to be better than its ranking. Louisville has blown out its past two opponents, and Jackson is running on all cylinders. Francois will have to play it cool in a hostile environment. Look for the Cardinals to pull off the upset and shake up the ACC. Pick: Louisville

SportsLine ATS projection: Louisville +1 — Analysis

Texas A&M at Auburn: Noel Mazzone’s system has been a dream come true for QB Trevor Knight. Knight has seen a resurgence in his career and has flashed the talent that made him a Sugar Bowl MVP at Oklahoma. The Aggies are looking to solidify their top 25 ranking after beating UCLA in the opening week. But Auburn QB Sean White has found his confidence after leading a more inspiring performance last week versus Arkansas State. Unfortunately for the Tigers, the Aggies have too much up front for the Auburn offensive line to handle. I like the Aggies in this one. Pick: Texas A&M

SportsLine ATS projection: Auburn -3.5 — Analysis

Ohio State at Oklahoma: The Buckeyes arrive in Norman with plenty on the line. With a tough Big Ten schedule, Ohio State can’t afford to lose to Oklahoma and hope to make it through the rest of the year unscathed. The Sooners also can’t afford to drop another game, otherwise their College Football Playoff hopes will be lost for good. The key to this matchup is whether the Sooners run the football and find success doing so. The Buckeyes have the personnel on defense to stop Samaje Perine and Joe Mixon, making QB Baker Mayfield is the wildcard — both through the air and on the ground. If he can make big plays, Oklahoma has a shot. The only issue is, well, who is he throwing it to? Mark Andrews and Dede Westbrook were supposed to take over for Sterling Shepherd, but that hasn’t quite happened yet. The Buckeyes have one of the best decision makers in the county in QB J.T. Barrett. Look for him to lead a young but talented team to victory. Pick: Ohio State

SportsLine ATS projection: Ohio State -1.5 — Analysis


Source: CBS Sports Headlines / College football picks: Brady Quinn makes calls on Week 3’s biggest games