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Colin Kaepernick owns the most popular jersey in the NFL right now-media-1105.5 THE TEAM – The Bills won’t have to worry about adjusting to a different time zone in Week 6 when the San Francisco 49ers com East to New Era Field, but they will face another challenge.

On Tuesday 49ers head coach Chip Kelly announced that after five weeks of miserable quarterbacking from Blaine Gabbert they will start controversial QB Colin Kaepernick on Sunday.

Kaepernick has become part of a national conversation, fueled by his kneeling during the national anthem in protest of numerous issues facing our country such as this year’s presidential candidates and the many injustices against African Americans.

It will be the first time Kaepernick starts for San Francisco since Week 8 of the 2015 campaign when he was benched by then head coach Tom Tomsula in favor of Gabbert.

Shortly after his benching he received surgery on his left shoulder to repair a torn labrum and was placed on the IR, then underwent two more procedures this past off-season on his throwing hand thumb and left knee, respectively.

The Nevada product most notably led the 49ers to a Super Bowl in 2012, falling to the Ravens after nearly orchestrating a game-winning drive in the closing minutes. Since that magical Lombardi chase concluded, Kaepernick has regressed significantly.

There’s plenty of film out there of the 28-year-old QB, but not it Kelly’s offense, which presents an interesting challenge for Rex Ryan and his defense to scheme for.

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